STAT2 Transcription Factor

A signal transducer and activator of transcription that mediates cellular responses to TYPE I INTERFERONS. Stat2 protein is associated constitutively with INTERFERON REGULATORY FACTOR-9. After PHOSPHORYLATION Stat2 forms the IFN-STIMULATED GENE FACTOR 3 COMPLEX to regulate expression of target GENES.

Also Known As:

STAT2 Protein; Signal Transducer and Activator of Transcription 2; Transcription Factor STAT2; Factor STAT2, Transcription; Transcription Factor, STAT2

Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Transcription Factors: 39842
    - STAT Transcription Factors: 46
      - STAT2 Transcription Factor: 25
    - Interferon-Stimulated Gene Factor 3: 12
      - alpha Subunit Interferon-Stimulated Gene Factor 3
        STAT2 Transcription Factor: 25
  - Carrier Proteins: 13306
    - Signal Transducing Adaptor Proteins
      - STAT Transcription Factors: 46
        STAT2 Transcription Factor: 25
      - Interferon-Stimulated Gene Factor 3: 12
        alpha Subunit Interferon-Stimulated Gene Factor 3
        STAT2 Transcription Factor: 25
  - DNA-Binding Proteins: 2079
    - Interferon-Stimulated Gene Factor 3: 12
      - alpha Subunit Interferon-Stimulated Gene Factor 3
        STAT2 Transcription Factor: 25
  - Intracellular Signaling Peptides and Proteins: 32
    - Signal Transducing Adaptor Proteins
      - STAT Transcription Factors: 46
        STAT2 Transcription Factor: 25
      - Interferon-Stimulated Gene Factor 3: 12
        alpha Subunit Interferon-Stimulated Gene Factor 3
        STAT2 Transcription Factor: 25
- Peptides: 84029
  - Intracellular Signaling Peptides and Proteins: 32
    - Signal Transducing Adaptor Proteins
      - STAT Transcription Factors: 46
        STAT2 Transcription Factor: 25
      - Interferon-Stimulated Gene Factor 3: 12
        alpha Subunit Interferon-Stimulated Gene Factor 3
        STAT2 Transcription Factor: 25

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Disease

Drug/Important Bio-Agent (IBA)